Alcoholic Neuropathy: Practice Essentials, Pathophysiology, Epidemiology

The histologic features of sural nerve biopsy specimens demonstrated small fibre predominant axonal loss as characteristic of the pure form of alcoholic neuropathy. Ethanol and its toxic metabolites affect neural metabolism including metabolic activities in the nucleus, lysosomes, peroxisomes, endoplasmic reticulum, and cytoplasm [104]. The morphological basis of post-alcoholic damage of neural tissue includes primary […]

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